Calories in Starbucks Cookies & Cream Frappuccino with semi-skimmed milk run 273 to 422 calories by size, identical to the low-fat and lactose-free versions — “semi-skimmed” is simply the UK term for that same lighter milk.
A Grande comes to 365 calories with fat at 18.4g and sodium at 308mg. Whichever regional name you use, the drink and the numbers stay exactly the same — only whole milk actually changes anything here.
For the American labeling, both low-fat and lactose-free milk pages carry these same numbers.
Cookies & Cream Frappuccino® - semi-skimmed milk Nutrition Facts
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Cookies & Cream Frappuccino® - semi-skimmed milk
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Long-Term Health Impact
After 1 Week
Drinking a daily Grande Cookies & Cream Frappuccino® - semi-skimmed milk adds 2555 calories to your week — about 491 minutes of brisk walking to offset.
After 1 Month
Over a month, that's 10950 calories — roughly 3.1 lb of potential weight gain if it isn't offset by activity.
After 1 Year
Over a year, a daily Grande Cookies & Cream Frappuccino® - semi-skimmed milk totals 133225 calories and 13.4kg of sugar — equivalent to about 1332 miles of jogging to burn off.

